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2016 ATRX Loss Promotes Tumor Growth and Impairs Non-Homologous End Joining DNA Repair in Glioma.

2010 Exogenous fms-like tyrosine kinase 3 ligand overrides brain immune privilege and facilitates recognition of a neo-antigen without causing autoimmune neuropathology.

Chair, American Society of Gene and Cell Therapy Neural Disorders Gene Therapy Committee, June 2009 — June 2010.

Koschmann C, Calinescu AA, Nunez FJ, Mackay A, Fazal-Salom J, Thomas D, Mulpuri L, Kamran N, Mendez F, Dzaman M, Krasinkiewicz J, Doherty R, Lemons R, Li Y, Roh S, Zhao L, Appleman H, Ferguson D, Gorbunova V, Meeker A, Jones C, Lowenstein PR, Castro MG.

2011-2014 Gutless Adenovirus Mediated Gene Therapy for Glioma S1: NIH• The Medallions Group Endowed Chair in Cancer Gene Therapeutics Research, Cedars-Sinai Medical Center, Los Angeles, California, USA, 2006.

Areas of Interest Research Focus Pediatric and adult brain cancer biology and therapeutics.

Current Research Activity Mutant IDH1 Glioma Project Glioma genetic models are needed to uncover mechanisms that mediate tumor progression, the interplay with the tumor microenvironment TME and response to therapeutics.

Featured in the Highlights Section.

Sanderson NS, Puntel M, Kroeger KM, Bondale NS, Swerdlow M, Iranmanesh N, Yagita H, Ibrahim A, Castro MG, Lowenstein PR.

Member, Program Organizing Committee, American Society of Cell and Gene Therapy, May 2011—June 2013.

Calinescu AA, Yadav VN, Carballo E, Kadiyala P, Tran D, Zamler D, Doherty R, Srikanth M, Lowenstein PR, Castro MG.

Clinical Cancer Research, 17 14 :4705-4718.